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Bone Marrow Karyotyping

Oncogenetics

Test Code: BONKAR

Genes: NA (0 genes)

Sample Type: Bone marrow volume depends on sample availability and calculated white cell count, and specimens may be submitted using heparinized syringes or sodium heparin vacutainers.

Method: GTW banding is performed on metaphase spreads

Turnaround Time: 2 weeks

Courier: Ship overnight at room temperature to receive next day. Do not refrigerate or freeze. Maintain specimen at room temperature.

Price: 900

Description:
Chromosome analysis of bone marrow is a key tool for assessing remission or relapse of malignancy and identifying abnormal clones, with a normal karyotype in conditions such as myelodysplastic syndrome, acute myeloid leukemia, acute lymphoblastic leukemia, or lymphoproliferative disorders generally serving as a favorable prognostic indicator; follow-up specimens may be submitted to monitor karyotypic evolution as the clinical course changes, and bone marrow is the preferred sample type over peripheral blood, with a minimum of 20 cells analyzed, while stimulated and unstimulated blood cultures are established only if peripheral blood is received alongside bone marrow, and stimulated blood cultures are examined only if bone marrow cultures fail, with GTW banding performed on metaphase spreads.